MedKoo Cat#: 124688 | Name: Teopranitol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Teopranitol, a coronary vasodilator, was studied for the treatment of the acute myocardial ischemia.

Chemical Structure

Teopranitol
Teopranitol
CAS#81792-35-0

Theoretical Analysis

MedKoo Cat#: 124688

Name: Teopranitol

CAS#: 81792-35-0

Chemical Formula: C16H22N6O7

Exact Mass: 410.1500

Molecular Weight: 410.39

Elemental Analysis: C, 46.83; H, 5.40; N, 20.48; O, 27.29

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Teopranitol; 81792-35-0; Teopranitolum; UNII-631R1KON85; 631R1KON85
IUPAC/Chemical Name
[(3S,3aR,6S,6aS)-3-[3-(1,3-dimethyl-2,6-dioxopurin-7-yl)propylamino]-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate
InChi Key
XTEGRRHNMFDROI-YRRQLQLVSA-N
InChi Code
InChI=1S/C16H22N6O7/c1-19-14-11(15(23)20(2)16(19)24)21(8-18-14)5-3-4-17-9-6-27-13-10(29-22(25)26)7-28-12(9)13/h8-10,12-13,17H,3-7H2,1-2H3/t9-,10-,12+,13+/m0/s1
SMILES Code
O=[N+]([O-])O[C@H]1CO[C@@]2([H])[C@]1([H])OC[C@@H]2NCCCN3C=NC(N(C)C(N4C)=O)=C3C4=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 410.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Thiemermann C, Smith EF 3rd, Schrör K. Successful treatment of acute myocardial ischaemia with teopranitol--a novel organic nitrate. Eur Heart J. 1986 May;7(5):418-24. doi: 10.1093/oxfordjournals.eurheartj.a062083. PMID: 3732290. 2: Darius H, Weiss P, Schrör K. Stereospecific stimulation of coronary vascular PGI2 by organic nitrates--studies with the new compound teopranitol (KC-046). Biomed Biochim Acta. 1984;43(8-9):S269-72. PMID: 6393969. 3: Engberding R, Tschakert H, Bender F, Rübe W. Anderungen szintigraphisch bestimmter regionaler Blutvolumina bei Koronarkranken unter dem Einfluss der neuen Substanz Teopranitol [Changes in scintigraphically determined regional blood volume in coronary patients treated with the new substance teopranitol]. Z Kardiol. 1984 Jun;73(6):370-3. German. PMID: 6475177. 4: Pohl U, Busse R. Endothelium-derived relaxant factor inhibits effects of nitrocompounds in isolated arteries. Am J Physiol. 1987 Feb;252(2 Pt 2):H307-13. doi: 10.1152/ajpheart.1987.252.2.H307. PMID: 3492925. 5: Schrör K, Ahland B, Weiss P, König E. Stimulation of coronary vascular PGI2 by organic nitrates. Eur Heart J. 1988 Jan;9 Suppl A:25-32. doi: 10.1093/eurheartj/9.suppl_a.25. PMID: 3137069. 6: Schrör K, Weiss P, Löbel P, Darius H, Latta G. Organische Nitrate und Prostaglandine im kardiovaskulären System [Organic nitrates and prostaglandins in the cardiovascular system]. Z Kardiol. 1986;75 Suppl 3:30-4. German. PMID: 3541416.