Synonym
Diciferron; Diciferron [INN]; Diciferronum; 3,5,5-Trimethylhexanoyl ferrocene; Diciferronum [INN-Latin]
IUPAC/Chemical Name
iron(II) 1-(cyclopenta-2,4-dien-1-ylidene)-3,5,5-trimethylhexan-1-olate cyclopenta-2,4-dien-1-ide
InChi Key
ACNAXEZQQXXWAE-UHFFFAOYSA-M
InChi Code
InChI=1S/C14H22O.C5H5.Fe/c1-11(10-14(2,3)4)9-13(15)12-7-5-6-8-12;1-2-4-5-3-1;/h5-8,11,15H,9-10H2,1-4H3;1-5H;/q;-1;+2/p-1
SMILES Code
CC(CC(=C1C=CC=C1)[O-])CC(C)(C)C.[CH-]1C=CC=C1.[Fe+2]
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
326.26
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Nielsen P, Heinrich HC. Metabolism of iron from
(3,5,5-trimethylhexanoyl)ferrocene in rats. A dietary model for severe iron
overload. Biochem Pharmacol. 1993 Jan 26;45(2):385-91. doi:
10.1016/0006-2952(93)90074-7. PMID: 8435091.
2: Malecki EA, Cable EE, Isom HC, Connor JR. The lipophilic iron compound TMH-
ferrocene [(3,5,5-trimethylhexanoyl)ferrocene] increases iron concentrations,
neuronal L-ferritin, and heme oxygenase in brains of BALB/c mice. Biol Trace
Elem Res. 2002 Apr;86(1):73-84. doi: 10.1385/BTER:86:1:73. PMID: 12002662.
3: Lykkesfeldt J, Morgan E, Christen S, Skovgaard LT, Moos T. Oxidative stress
and damage in liver, but not in brain, of Fischer 344 rats subjected to dietary
iron supplementation with lipid-soluble [(3,5,5-trimethylhexanoyl)ferrocene]. J
Biochem Mol Toxicol. 2007;21(3):145-55. doi: 10.1002/jbt.20170. PMID: 17623885.