Baquiloprim | veterinary medicine | sulphadimidine | diarrhea | CAS#102280-35-3

MedKoo Cat#: 124646 | Name: Baquiloprim

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Baquiloprim, a drug that was used in veterinary medicine, e.g. in combination with sulphadimidine for the treatment of diarrhea in calves.

Chemical Structure

Baquiloprim

CAS#102280-35-3

Theoretical Analysis

MedKoo Cat#: 124646

Name: Baquiloprim

CAS#: 102280-35-3

Chemical Formula: C17H20N6

Exact Mass: 308.1700

Molecular Weight: 308.39

Elemental Analysis: C, 66.21; H, 6.54; N, 27.25

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Baquiloprim; 102280-35-3; Baquiloprima; Baquiloprime; Baquiloprimum;

IUPAC/Chemical Name

5-((8-(dimethylamino)-7-methylquinolin-5-yl)methyl)pyrimidine-2,4-diamine

InChi Key

AIOWJIMWVFWROP-UHFFFAOYSA-N

InChi Code

InChI=1S/C17H20N6/c1-10-7-11(8-12-9-21-17(19)22-16(12)18)13-5-4-6-20-14(13)15(10)23(2)3/h4-7,9H,8H2,1-3H3,(H4,18,19,21,22)

SMILES Code

CC1=CC(=C2C=CC=NC2=C1N(C)C)CC3=CN=C(N=C3N)N

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 308.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: White G, Daluge SM, Sigel CW, Ferone R, Wilson HR. Baquiloprim, a new antifolate antibacterial: in vitro activity and pharmacokinetic properties in cattle. Res Vet Sci. 1993 May;54(3):372-8. doi: 10.1016/0034-5288(93)90138-6. PMID: 8337486. 2: White DG, Johnson CK, Cracknell V. Comparison of danofloxacin with baquiloprim/sulphadimidine for the treatment of experimentally induced Escherichia coli diarrhoea in calves. Vet Rec. 1998 Sep 5;143(10):273-6. doi: 10.1136/vr.143.10.273. PMID: 9787420. 3: Svensson C. Prevention of Eimeria alabamensis coccidiosis by a long-acting baquiloprim/sulphadimidine bolus. Vet Parasitol. 1998 Jan 31;74(2-4):143-52. doi: 10.1016/s0304-4017(97)00154-4. PMID: 9561702. 4: Lewicki J, Maas RF, Witkamp RF, Van-Miert AS. Oral bioavailability and pharmacokinetics of baquiloprim in dwarf goats. Res Vet Sci. 1995 May;58(3):268-71. doi: 10.1016/0034-5288(95)90115-9. PMID: 7659854. 5: Davies AM, MacKenzie NM. Pharmacokinetics of baquiloprim and sulphadimidine in pigs after intramuscular administration. Res Vet Sci. 1994 Jul;57(1):69-74. doi: 10.1016/0034-5288(94)90084-1. PMID: 7973096.