MedKoo Cat#: 124613 | Name: 5-LOX-IN-2
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

5-LOX-IN-2 is an inhibitor of 5-lipoxygenase (5-LOX). 5-LOX-IN-2, reduces the cell viability of renal cancer cells and induces apoptosis, can be used for cancer research.

Chemical Structure

5-LOX-IN-2
5-LOX-IN-2
CAS#179691-97-5

Theoretical Analysis

MedKoo Cat#: 124613

Name: 5-LOX-IN-2

CAS#: 179691-97-5

Chemical Formula: C17H16O4

Exact Mass: 284.1049

Molecular Weight: 284.31

Elemental Analysis: C, 71.82; H, 5.67; O, 22.51

Price and Availability

Size Price Availability Quantity
100mg USD 1,350.00 2 Weeks
200mg USD 2,050.00 2 Weeks
500mg USD 3,250.00 2 Weeks
1g USD 4,650.00 2 Weeks
2g USD 6,950.00 2 Weeks
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Related CAS #
No Data
Synonym
5LOX-IN-2; 5-LOX-IN2; 5-LOX-IN-2
IUPAC/Chemical Name
phenethyl (E)-3-(2,5-dihydroxyphenyl)acrylate
InChi Key
OQKRMXDGEFRBAJ-RMKNXTFCSA-N
InChi Code
InChI=1S/C17H16O4/c18-15-7-8-16(19)14(12-15)6-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-6+
SMILES Code
O=C(OCCC1=CC=CC=C1)/C=C/C2=CC(O)=CC=C2O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 284.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Selka A, Doiron JA, Lyons P, Dastous S, Chiasson A, Cormier M, Turcotte S, Surette ME, Touaibia M. Discovery of a novel 2,5-dihydroxycinnamic acid-based 5-lipoxygenase inhibitor that induces apoptosis and may impair autophagic flux in RCC4 renal cancer cells. Eur J Med Chem. 2019 Oct 1;179:347-357. doi: 10.1016/j.ejmech.2019.06.060. Epub 2019 Jun 23. PMID: 31260889.