MedKoo Cat#: 124603 | Name: HDAC-IN-58
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

HDAC-IN-58 is a HDAC inhibitor.

Chemical Structure

HDAC-IN-58
HDAC-IN-58
CAS#2071224-39-8

Theoretical Analysis

MedKoo Cat#: 124603

Name: HDAC-IN-58

CAS#: 2071224-39-8

Chemical Formula: C16H13ClF2N4O3S

Exact Mass: 414.0365

Molecular Weight: 414.81

Elemental Analysis: C, 46.33; H, 3.16; Cl, 8.55; F, 9.16; N, 13.51; O, 11.57; S, 7.73

Price and Availability

Size Price Availability Quantity
100mg USD 1,350.00 2 Weeks
200mg USD 2,050.00 2 Weeks
500mg USD 3,250.00 2 Weeks
1g USD 4,650.00 2 Weeks
2g USD 6,950.00 2 Weeks
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Related CAS #
No Data
Synonym
HDAC-IN-58; HDAC-IN 58; HDAC-IN58; HDAC IN-58
IUPAC/Chemical Name
N-(3-chlorophenyl)-N-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)pyridin-2-yl)methyl)methanesulfonamide
InChi Key
FPBMSTFEAXNETL-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H13ClF2N4O3S/c1-27(24,25)23(13-4-2-3-11(17)7-13)9-12-6-5-10(8-20-12)15-21-22-16(26-15)14(18)19/h2-8,14H,9H2,1H3
SMILES Code
CS(=O)(N(C1=CC=CC(Cl)=C1)CC2=NC=C(C3=NN=C(C(F)F)O3)C=C2)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 414.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Motlová L, Šnajdr I, Kutil Z, Andris E, Ptáček J, Novotná A, Nováková Z, Havlínová B, Tueckmantel W, Dráberová H, Majer P, Schutkowski M, Kozikowski A, Rulíšek L, Bařinka C. Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6). ACS Chem Biol. 2023 Jul 21;18(7):1594-1610. doi: 10.1021/acschembio.3c00212. Epub 2023 Jul 1. PMID: 37392419; PMCID: PMC10367051.