MedKoo Cat#: 124437 | Name: HYNIC-FAPI-04
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

HYNIC-FAPI-04 is a useful ligand for making [99mTc]Tc-HYNIC-FAPI-04. In vitro experiments, the results indicated that [99mTc]Tc-HYNIC-FAPI-04 showed binding properties, and inhibited the migration of tumor cells. The [99mTc]Tc-HYNIC-FAPI will be a promising SPECT/CT imaging probe.

Chemical Structure

HYNIC-FAPI-04
HYNIC-FAPI-04
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 124437

Name: HYNIC-FAPI-04

CAS#: N/A

Chemical Formula: C30H33F2N9O4

Exact Mass: 621.2624

Molecular Weight: 621.65

Elemental Analysis: C, 57.96; H, 5.35; F, 6.11; N, 20.28; O, 10.29

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 Ready to ship
2mg USD 550.00 Ready to ship
5mg USD 950.00 Ready to ship
10mg USD 1,550.00 Ready to ship
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Related CAS #
No Data
Synonym
HYNIC-FAPI-04; EX-A5970; HYNIC FAPI-04; HYNIC-FAPI 04; HYNIC FAPI 04; HYNIC-FAPI-4
IUPAC/Chemical Name
(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)-6-(3-(4-(6-hydrazinylnicotinoyl)piperazin-1-yl)propoxy)quinoline-4-carboxamide
InChi Key
XAWLVMKVOYTLEL-NRFANRHFSA-N
InChi Code
InChI=1S/C30H33F2N9O4/c31-30(32)15-21(16-33)41(19-30)27(42)18-37-28(43)23-6-7-35-25-4-3-22(14-24(23)25)45-13-1-8-39-9-11-40(12-10-39)29(44)20-2-5-26(38-34)36-17-20/h2-7,14,17,21H,1,8-13,15,18-19,34H2,(H,36,38)(H,37,43)/t21-/m0/s1
SMILES Code
O=C(NCC(N1[C@@H](CC(F)(C1)F)C#N)=O)C2=CC=NC3=CC=C(C=C23)OCCCN4CCN(CC4)C(C5=CN=C(C=C5)NN)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 621.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Luo X, Zhang Z, Cheng C, Wang T, Fang D, Zuo C, Yuan G, Li R, Li X. SPECT Imaging with Tc-99m-Labeled HYNIC-FAPI-04 to Extend the Differential Time Window in Evaluating Tumor Fibrosis. Pharmaceuticals (Basel). 2023 Mar 10;16(3):423. doi: 10.3390/ph16030423. PMID: 36986521; PMCID: PMC10051245.