MedKoo Cat#: 124248 | Name: PYZ18
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

PYZ18 is a selective COX-2 inhibitor.

Chemical Structure

PYZ18
PYZ18
CAS#1447578-01-9

Theoretical Analysis

MedKoo Cat#: 124248

Name: PYZ18

CAS#: 1447578-01-9

Chemical Formula: C18H14F3N3S

Exact Mass: 361.0861

Molecular Weight: 361.39

Elemental Analysis: C, 59.82; H, 3.90; F, 15.77; N, 11.63; S, 8.87

Price and Availability

Size Price Availability Quantity
100mg USD 750.00 2 Weeks
200mg USD 1,250.00 2 Weeks
500mg USD 2,650.00 2 Weeks
1g USD 3,850.00 2 Weeks
2g USD 5,950.00 2 Weeks
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Related CAS #
No Data
Synonym
PYZ18; PYZ 18; PYZ-18
IUPAC/Chemical Name
4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzothioamide
InChi Key
DLUIPPLWXZORGW-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H14F3N3S/c1-11-2-4-12(5-3-11)15-10-16(18(19,20)21)23-24(15)14-8-6-13(7-9-14)17(22)25/h2-10H,1H3,(H2,22,25)
SMILES Code
FC(F)(C1=NN(C(C2=CC=C(C)C=C2)=C1)C3=CC=C(C(N)=S)C=C3)F
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 361.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Chahal S, Rani P, Kiran, Sindhu J, Joshi G, Ganesan A, Kalyaanamoorthy S, Mayank, Kumar P, Singh R, Negi A. Design and Development of COX-II Inhibitors: Current Scenario and Future Perspective. ACS Omega. 2023 May 9;8(20):17446-17498. doi: 10.1021/acsomega.3c00692. PMID: 37251190; PMCID: PMC10210234.