MedKoo Cat#: 124229 | Name: TRK-IN-22
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TRK-IN-22 (compound 11) is a TRK inhibitor.

Chemical Structure

TRK-IN-22
TRK-IN-22
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 124229

Name: TRK-IN-22

CAS#: N/A

Chemical Formula: C17H14ClFN4

Exact Mass: 328.0891

Molecular Weight: 328.78

Elemental Analysis: C, 62.11; H, 4.29; Cl, 10.78; F, 5.78; N, 17.04

Price and Availability

Size Price Availability Quantity
100mg USD 1,250.00 2 Weeks
200mg USD 2,050.00 2 Weeks
500mg USD 3,250.00 2 Weeks
1g USD 4,250.00 2 Weeks
2g USD 6,550.00 2 Weeks
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Related CAS #
No Data
Synonym
TRK-IN-22; TRK-IN22; TRK-IN 22; Compound 11
IUPAC/Chemical Name
5-chloro-N4-(3-fluorobenzyl)-N2-phenylpyrimidine-2,4-diamine
InChi Key
AMSRGKDNWGDDLR-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H14ClFN4/c18-15-11-21-17(22-14-7-2-1-3-8-14)23-16(15)20-10-12-5-4-6-13(19)9-12/h1-9,11H,10H2,(H2,20,21,22,23)
SMILES Code
FC1=CC(CNC2=C(C=NC(NC3=CC=CC=C3)=N2)Cl)=CC=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 328.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Wu T, Qin Q, Liu N, Zhang C, Lv R, Yin W, Sun Y, Sun Y, Wang R, Zhao D, Cheng M. Rational drug design to explore the structure-activity relationship (SAR) of TRK inhibitors with 2,4-diaminopyrimidine scaffold. Eur J Med Chem. 2022 Feb 15;230:114096. doi: 10.1016/j.ejmech.2021.114096. Epub 2022 Jan 3. PMID: 35007864.