AZD4747 is a Potent and Selective Inhibitor of Mutant GTPase KRASG12C with Demonstrable CNS Penetration. AZD4747 is a clinical development candidate for the treatment of KRASG12C-positive tumors, including the treatment of central nervous system (CNS) metastases.
MedKoo Cat#: 124133
Name: AZD4747
CAS#: 2489226-14-2
Chemical Formula: C24H22ClFN2O3
Exact Mass: 440.1303
Molecular Weight: 440.90
Elemental Analysis: C, 65.38; H, 5.03; Cl, 8.04; F, 4.31; N, 6.35; O, 10.89
The following data is based on the product molecular weight 440.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
