DDO-8926 is a BET inhibitor. DDO-8926 exhibits excellent BET selectivity and favorable drug-like properties. In mice with spared nerve injury, DDO-8926 significantly alleviated mechanical hypersensitivity by inhibiting pro-inflammatory cytokine expression and reducing excitability. DDO-8926 is a promising agent for the treatment of neuropathic pain .
MedKoo Cat#: 124066
Name: DDO-8926
CAS#: N/A
Chemical Formula: C20H21FN6O2S
Exact Mass: 428.1400
Molecular Weight: 428.49
Elemental Analysis: C, 56.06; H, 4.94; F, 4.43; N, 19.61; O, 7.47; S, 7.48
The following data is based on the product molecular weight 428.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
