MedKoo Cat#: 124035 | Name: STAT3-IN-15
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

STAT3-IN-15 is a potent and orally active STAT3 inhibitor.

Chemical Structure

STAT3-IN-15
STAT3-IN-15
CAS#3037596-35-0

Theoretical Analysis

MedKoo Cat#: 124035

Name: STAT3-IN-15

CAS#: 3037596-35-0

Chemical Formula: C20H17F3N2O3S

Exact Mass: 422.0912

Molecular Weight: 422.42

Elemental Analysis: C, 56.87; H, 4.06; F, 13.49; N, 6.63; O, 11.36; S, 7.59

Price and Availability

Size Price Availability Quantity
100mg USD 1,450.00 2 Weeks
200mg USD 2,150.00 2 Weeks
500mg USD 3,650.00 2 Weeks
1g USD 5,650.00 2 Weeks
2g USD 7,850.00 2 Weeks
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Related CAS #
No Data
Synonym
STAT3-IN-16; STAT3-IN-15; STAT3-IN 15; STAT3 IN-15
IUPAC/Chemical Name
(1,1-dioxidobenzo[b]thiophen-2-yl)(4-(2,4,5-trifluorobenzyl)piperazin-1-yl)methanone
InChi Key
MSOPUAJZYRMAJX-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H17F3N2O3S/c21-15-11-17(23)16(22)9-14(15)12-24-5-7-25(8-6-24)20(26)19-10-13-3-1-2-4-18(13)29(19,27)28/h1-4,9-11H,5-8,12H2
SMILES Code
C1CN(CCN1CC2=CC(=C(C=C2F)F)F)C(=O)C3=CC4=CC=CC=C4S3(=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 422.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Wang Y, Liu H, Li W, Xie Y, Gan C, Xue T, Su X, Yue L, Wang Q, Fan C, Zhang Y, Ye T. Discovery of the novel Benzo[b]thiophene 1,1-dioxide derivatives as a potent STAT3 inhibitor against idiopathic pulmonary fibrosis. Eur J Med Chem. 2023 Jan 15;246:114953. doi: 10.1016/j.ejmech.2022.114953. Epub 2022 Nov 28. PMID: 36463728.