VU0506013 is a High-Affinity Neuropeptide Y4 Receptor Positive Allosteric Modulator (PAM). VU0506013 exhibits nanomolar affinity and pronounced selectivity toward the Y4R in engineered cell lines and mouse descending colon mucosa natively expressing the Y4R. VU0506013 presents a promising scaffold for developing in vivo tools to move toward anti-obesity drug research focused on the Y4R.
MedKoo Cat#: 123998
Name: VU0506013
CAS#: 1207036-87-0
Chemical Formula: C20H23N3O4
Exact Mass: 369.1700
Molecular Weight: 369.42
Elemental Analysis: C, 65.03; H, 6.28; N, 11.37; O, 17.32
The following data is based on the product molecular weight 369.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
