TUG-2465 | SUCNR1 agonist

MedKoo Cat#: 123956 | Name: TUG-2465

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TUG-2465 is a potent SUCNR1 agonist. tracer, The succinate receptor (SUCNR1) has emerged as a potential target for the treatment of various metabolic and inflammatory diseases, including hypertension, inflammatory bowel disease, and rheumatoid arthritis.

Chemical Structure

TUG-2465

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 123956

Name: TUG-2465

CAS#: N/A

Chemical Formula: C35H35N7O6

Exact Mass: 649.2600

Molecular Weight: 649.71

Elemental Analysis: C, 64.70; H, 5.43; N, 15.09; O, 14.77

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

TUG-2465; TUG 2465; TUG2465

IUPAC/Chemical Name

2-(2-(2'-methyl-4'-((4-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)ethyl)piperazin-1-yl)methyl)-[1,1'-biphenyl]-3-carboxamido)phenyl)acetic acid

InChi Key

IRYPJZWXCBPWNC-UHFFFAOYSA-N

InChi Code

InChI=1S/C35H35N7O6/c1-23-19-24(9-10-28(23)25-6-4-7-27(20-25)35(45)37-29-8-3-2-5-26(29)21-32(43)44)22-41-17-15-40(16-18-41)14-13-36-30-11-12-31(42(46)47)34-33(30)38-48-39-34/h2-12,19-20,36H,13-18,21-22H2,1H3,(H,37,45)(H,43,44)

SMILES Code

OC(CC1=C(NC(C2=CC=CC(C3=CC=C(CN4CCN(CCNC5=CC=C([N+]([O-])=O)C6=NON=C65)CC4)C=C3C)=C2)=O)C=CC=C1)=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 649.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Ciba M, Dibnah B, Hudson BD, Rexen Ulven E. Development and Characterization of Potent Succinate Receptor Fluorescent Tracers. J Med Chem. 2023 Jun 15. doi: 10.1021/acs.jmedchem.3c00552. Epub ahead of print. PMID: 37318348.