MedKoo Cat#: 123955 | Name: TUG-2384

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TUG-2384 is a potent SUCNR1 agonist. tracer, TUG-2384 has high affinity for both human and mouse SUCNR1. The succinate receptor (SUCNR1) has emerged as a potential target for the treatment of various metabolic and inflammatory diseases, including hypertension, inflammatory bowel disease, and rheumatoid arthritis.

Chemical Structure

TUG-2384
TUG-2384
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 123955

Name: TUG-2384

CAS#: N/A

Chemical Formula: C29H32N6O10

Exact Mass: 624.2200

Molecular Weight: 624.61

Elemental Analysis: C, 55.77; H, 5.16; N, 13.46; O, 25.61

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
TUG-2384; TUG 2384; TUG2384
IUPAC/Chemical Name
(5-(4-((6-((2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)ethyl)amino)hexyl)oxy)phenyl)furan-2-carbonyl)-L-aspartic acid
InChi Key
TWPXTGCZPCWJLY-NRFANRHFSA-N
InChi Code
InChI=1S/C29H32N6O10/c36-25(37)17-21(29(39)40)32-28(38)24-12-11-23(44-24)18-5-7-19(8-6-18)43-16-4-2-1-3-13-30-14-15-31-20-9-10-22(35(41)42)27-26(20)33-45-34-27/h5-12,21,30-31H,1-4,13-17H2,(H,32,38)(H,36,37)(H,39,40)/t21-/m0/s1
SMILES Code
O=[N+](C1=CC=C(NCCNCCCCCCOC2=CC=C(C3=CC=C(C(N[C@H](C(O)=O)CC(O)=O)=O)O3)C=C2)C4=NON=C41)[O-]
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 624.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Ciba M, Dibnah B, Hudson BD, Rexen Ulven E. Development and Characterization of Potent Succinate Receptor Fluorescent Tracers. J Med Chem. 2023 Jun 15. doi: 10.1021/acs.jmedchem.3c00552. Epub ahead of print. PMID: 37318348.