MedKoo Cat#: 123923 | Name: PARP-1-IN-4
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

PARP-1-IN-4 is a PARP-1 inhibitor.

Chemical Structure

PARP-1-IN-4
PARP-1-IN-4
CAS#684234-56-8

Theoretical Analysis

MedKoo Cat#: 123923

Name: PARP-1-IN-4

CAS#: 684234-56-8

Chemical Formula: C22H15Cl2N3O2

Exact Mass: 423.0541

Molecular Weight: 424.28

Elemental Analysis: C, 62.28; H, 3.56; Cl, 16.71; N, 9.90; O, 7.54

Price and Availability

Size Price Availability Quantity
100mg USD 950.00 2 Weeks
200mg USD 1,450.00 2 Weeks
500mg USD 2,850.00 2 Weeks
1g USD 3,850.00 2 Weeks
2g USD 6,250.00 2 Weeks
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Related CAS #
No Data
Synonym
PARP-1-IN-4; PARP1-IN-4; PARP-1-IN4; PARP-1IN-4
IUPAC/Chemical Name
N-(4-chlorophenyl)-2-(4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl)acetamide
InChi Key
ZYDMHJZNLFTYOR-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H15Cl2N3O2/c23-15-7-5-14(6-8-15)21-18-3-1-2-4-19(18)22(29)27(26-21)13-20(28)25-17-11-9-16(24)10-12-17/h1-12H,13H2,(H,25,28)
SMILES Code
O=C(CN1N=C(C2=C(C1=O)C=CC=C2)C3=CC=C(Cl)C=C3)NC4=CC=C(C=C4)Cl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 424.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Almahli H, Hadchity E, Jaballah MY, Daher R, Ghabbour HA, Kabil MM, Al-Shakliah NS, Eldehna WM. Development of novel synthesized phthalazinone-based PARP-1 inhibitors with apoptosis inducing mechanism in lung cancer. Bioorg Chem. 2018 Apr;77:443-456. doi: 10.1016/j.bioorg.2018.01.034. Epub 2018 Feb 7. PMID: 29453076.