MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 130606 | Name: JNJ-47909290

Description:

WARNING: This product is for research use only, not for human or veterinary use.

JNJ-47909290 is a novel antagonist of CCR2.

Chemical Structure

JNJ-47909290
JNJ-47909290
CAS#JNJ-47909290

Theoretical Analysis

MedKoo Cat#: 130606

Name: JNJ-47909290

CAS#: JNJ-47909290

Chemical Formula: C23H30F3N3O4

Exact Mass: 469.2188

Molecular Weight: 469.51

Elemental Analysis: C, 58.84; H, 6.44; F, 12.14; N, 8.95; O, 13.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
JNJ 47909290, JNJ47909290, BDBM 50011986, BDBM-50011986
IUPAC/Chemical Name
((3aS,5S,6aR)-5-((3S,4S)-3-Methoxytetrahydro-2H-pyran-4-ylamino)hexahydro-2H-cyclopenta[b]furan-3a-yl)(3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)methanone
InChi Key
QOVXPTCADXFNFV-NEHCWNBQSA-N
InChi Code
InChI=1S/C23H30F3N3O4/c1-31-19-13-32-6-3-18(19)28-16-9-20-22(10-16,4-7-33-20)21(30)29-5-2-17-14(12-29)8-15(11-27-17)23(24,25)26/h8,11,16,18-20,28H,2-7,9-10,12-13H2,1H3/t16-,18+,19-,20-,22-/m1/s1
SMILES Code
O=C([C@]1(C[C@H](N[C@@H]2[C@H](OC)COCC2)C3)[C@]3([H])OCC1)N4CC5=C(N=CC(C(F)(F)F)=C5)CC4
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 469.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Winters MP, Teleha CA, Kang FA, McComsey D, O'Neill JC, Hou C, Kirchner T, Wang P, Johnson D, Sui Z. The discovery and SAR of cyclopenta[b]furans as inhibitors of CCR2. Bioorg Med Chem Lett. 2014 May 1;24(9):2137-40. doi: 10.1016/j.bmcl.2014.03.036. Epub 2014 Mar 22. PMID: 24685539.