Synonym
1 Palmitoyl LPA, 16:0-LPA, 1-Palmitoyl lysophosphatidic acid, 1-Palmitoylglycerol 3-phosphate, 1-Palmitoyl LPA acid, 1-Palmitoyl LPA
IUPAC/Chemical Name
(2-hydroxy-3-phosphonooxypropyl) hexadecanoate
InChi Key
YNDYKPRNFWPPFU-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H39O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(21)25-16-18(20)17-26-27(22,23)24/h18,20H,2-17H2,1H3,(H2,22,23,24)
SMILES Code
CCCCCCCCCCCCCCCC(OCC(O)COP(O)(O)=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, DMF, ethanol, and PBS
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
410.49
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1. Kuwata S, Ohkubo K, Kumamoto S, Yamaguchi N, Izuka N, Murota K, Tsujiuchi T, Iwamori M, Fukushima N. Extracellular lipid metabolism influences the survival of ovarian cancer cells. Biochem Biophys Res Commun. 2013 Sep 20;439(2):280-4. doi: 10.1016/j.bbrc.2013.08.041. Epub 2013 Aug 21. PMID: 23973712.
2. Liu XW, Sok DE, Yook HS, Sohn CB, Chung YJ, Kim MR. Inhibition of lysophospholipase D activity by unsaturated lysophosphatidic acids or seed extracts containing 1-linoleoyl and 1-oleoyl lysophosphatidic acid. J Agric Food Chem. 2007 Oct 17;55(21):8717-22. doi: 10.1021/jf071080u. Epub 2007 Sep 24. PMID: 17887800.
3. Minnear FL, Patil S, Bell D, Gainor JP, Morton CA. Platelet lipid(s) bound to albumin increases endothelial electrical resistance: mimicked by LPA. Am J Physiol Lung Cell Mol Physiol. 2001 Dec;281(6):L1337-44. doi: 10.1152/ajplung.2001.281.6.L1337. PMID: 11704528.