MedKoo Cat#: 130519 | Name: Biofilm inhibitor 2B5

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Biofilm inhibitor 2B5 is a novel and potent inhibitor of S. mutans biofilms (IC50 of 1.9 μM), targeting VicR, a key response regulator in S. mutans and S. aureus.

Chemical Structure

Biofilm inhibitor 2B5
Biofilm inhibitor 2B5
CAS#Biofilm inhibitor 2B5

Theoretical Analysis

MedKoo Cat#: 130519

Name: Biofilm inhibitor 2B5

CAS#: Biofilm inhibitor 2B5

Chemical Formula: C23H45ClN4O

Exact Mass: 428.3282

Molecular Weight: 429.09

Elemental Analysis: C, 64.38; H, 10.57; Cl, 8.26; N, 13.06; O, 3.73

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Biofilm inhibitor-2B5, Biofilm-In-2B5, Biofilm In 2B5, 2B5, Biofilm 2B5, Biofilm-2B5
IUPAC/Chemical Name
4-(2-Amino-1H-imidazol-4-yl)-N-hexadecylbutanamide hydrochloride
InChi Key
CTERFFVFQKDASL-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H44N4O.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-25-22(28)18-16-17-21-20-26-23(24)27-21;/h20H,2-19H2,1H3,(H,25,28)(H3,24,26,27);1H
SMILES Code
O=C(NCCCCCCCCCCCCCCCC)CCCC1=CNC(N)=N1.[H]Cl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 429.09 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Liu C, Zhang H, Peng X, Blackledge MS, Furlani RE, Li H, Su Z, Melander RJ, Melander C, Michalek S, Wu H. Small Molecule Attenuates Bacterial Virulence by Targeting Conserved Response Regulator. mBio. 2023 Apr 19:e0013723. doi: 10.1128/mbio.00137-23. Epub ahead of print. PMID: 37074183. 2. Liu C, Worthington RJ, Melander C, Wu H. A new small molecule specifically inhibits the cariogenic bacterium Streptococcus mutans in multispecies biofilms. Antimicrob Agents Chemother. 2011 Jun;55(6):2679-87. doi: 10.1128/AAC.01496-10. Epub 2011 Mar 14. PMID: 21402858; PMCID: PMC3101470.