MedKoo Cat#: 556339 | Name: TUG-499
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) (Free Fatty Acid Receptor) agonist

Chemical Structure

TUG-499
TUG-499
CAS#1206629-08-4

Theoretical Analysis

MedKoo Cat#: 556339

Name: TUG-499

CAS#: 1206629-08-4

Chemical Formula: C16H11Cl2NO2

Exact Mass: 319.0167

Molecular Weight: 320.17

Elemental Analysis: C, 60.02; H, 3.46; Cl, 22.14; N, 4.37; O, 9.99

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
200mg USD 1,250.00 2 Weeks
500mg USD 2,650.00 2 Weeks
1g USD 3,650.00 2 Weeks
2g USD 5,650.00 2 Weeks
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Related CAS #
No Data
Synonym
TUG-499; TUG 499; TUG499;
IUPAC/Chemical Name
3-(4-((2,6-dichloropyridin-4-yl)ethynyl)phenyl)propanoic acid
InChi Key
GCWBKYDSSJIRNJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H11Cl2NO2/c17-14-9-13(10-15(18)19-14)6-5-11-1-3-12(4-2-11)7-8-16(20)21/h1-4,9-10H,7-8H2,(H,20,21)
SMILES Code
O=C(O)CCC1=CC=C(C#CC2=CC(Cl)=NC(Cl)=C2)C=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 320.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Hagesaether E, Christiansen E, Due-Hansen ME, Ulven T. Mucus can change the permeation rank order of drug candidates. Int J Pharm. 2013 Aug 16;452(1-2):276-82. doi: 10.1016/j.ijpharm.2013.05.036. Epub 2013 May 23. PMID: 23707884. Christiansen E, Urban C, Grundmann M, Due-Hansen ME, Hagesaether E, Schmidt J, Pardo L, Ullrich S, Kostenis E, Kassack M, Ulven T. Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties. J Med Chem. 2011 Oct 13;54(19):6691-703. doi: 10.1021/jm2005699. Epub 2011 Sep 13. PMID: 21854074.