Lactoferrin acetate | CAS# 2828433-30-1 | Glycoprotein

MedKoo Cat#: 130503 | Name: Lactoferrin acetate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lactoferrin acetate is a natural globular glycoprotein of the immune system of the body and has antimicrobial activity against a wide range of microorganisms.

Chemical Structure

Lactoferrin acetate

CAS#2828433-30-1

Theoretical Analysis

MedKoo Cat#: 130503

Name: Lactoferrin acetate

CAS#: 2828433-30-1

Chemical Formula: C143H228N46O31S3

Exact Mass: 3181.6841

Molecular Weight: 3183.87

Elemental Analysis: C, 53.95; H, 7.22; N, 20.24; O, 15.58; S, 3.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Lactoferrin-acetate

IUPAC/Chemical Name

H-Phe-Lys-Cys(1)-Arg-Arg-Trp-Gln-Trp-Arg-Met-Lys-Lys-Leu-Gly-Ala-Pro-Ser-Ile-Thr-Cys(1)-Val-Arg-Arg-Ala-Phe-OH 8 AcOH

InChi Key

VODWFGYAYSDZHD-BSKQQEKQSA-N

InChi Code

InChI=1S/C141H224N46O29S3.C2H4O2/c1-11-77(6)111-133(212)186-112(80(9)189)134(213)183-106(130(209)184-110(76(4)5)132(211)176-97(49-32-61-161-141(155)156)120(199)170-93(45-28-57-157-137(147)148)116(195)166-78(7)113(192)180-103(136(215)216)66-82-36-16-13-17-37-82)74-219-218-73-105(182-123(202)90(42-22-25-54-142)167-114(193)87(145)65-81-34-14-12-15-35-81)129(208)173-95(47-30-59-159-139(151)152)118(197)171-96(48-31-60-160-140(153)154)122(201)178-102(68-84-70-163-89-41-21-19-39-86(84)89)127(206)174-98(51-52-108(146)190)124(203)179-101(67-83-69-162-88-40-20-18-38-85(83)88)126(205)172-94(46-29-58-158-138(149)150)119(198)175-99(53-63-217-10)125(204)169-91(43-23-26-55-143)117(196)168-92(44-24-27-56-144)121(200)177-100(64-75(2)3)115(194)164-71-109(191)165-79(8)135(214)187-62-33-50-107(187)131(210)181-104(72-188)128(207)185-111;1-2(3)4/h12-21,34-41,69-70,75-80,87,90-107,110-112,162-163,188-189H,11,22-33,42-68,71-74,142-145H2,1-10H3,(H2,146,190)(H,164,194)(H,165,191)(H,166,195)(H,167,193)(H,168,196)(H,169,204)(H,170,199)(H,171,197)(H,172,205)(H,173,208)(H,174,206)(H,175,198)(H,176,211)(H,177,200)(H,178,201)(H,179,203)(H,180,192)(H,181,210)(H,182,202)(H,183,213)(H,184,209)(H,185,207)(H,186,212)(H,215,216)(H4,147,148,157)(H4,149,150,158)(H4,151,152,159)(H4,153,154,160)(H4,155,156,161);1H3,(H,3,4)/t77-,78-,79-,80+,87-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,110-,111-,112-;/m0./s1

SMILES Code

CC[C@@H]([C@H]1C(N[C@@H]([C@H](O)C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)C)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)C(C)C)=O)CSSC[C@H](NC([C@@H](NC([C@@H](N)CC3=CC=CC=C3)=O)CCCCN)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC4=CNC5=CC=CC=C54)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC6=CNC7=CC=CC=C76)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCSC)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](C)C(N8CCC[C@H]8C(N[C@@H](CO)C(N1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C.CC(O)=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 3,183.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Kaczyńska K, Jampolska M, Wojciechowski P, Sulejczak D, Andrzejewski K, Zając D. Potential of Lactoferrin in the Treatment of Lung Diseases. Pharmaceuticals (Basel). 2023 Jan 28;16(2):192. doi: 10.3390/ph16020192. PMID: 37259341. 2. Masson PL, Heremans JF, Ferin J. Presence of an Iron-binding protein (lactoferrin) in the genital tract of the human female. I. Its immunohistochemical localization in the endometrium. Fertil Steril. 1968 Sep-Oct;19(5):679-89. doi: 10.1016/s0015-0282(16)36781-4. PMID: 4877677. 3. Masson P, Heremans JF, Prignot J. Immunohistochemical localization of the iron-binding protein lactoferrin in human bronchial glands. Experientia. 1965 Oct 15;21(10):604-5. doi: 10.1007/BF02151559. PMID: 5330250. 4. Yamauchi K, Wakabayashi H, Shin K, Takase M. Bovine lactoferrin: benefits and mechanism of action against infections. Biochem Cell Biol. 2006 Jun;84(3):291-6. doi: 10.1139/o06-054. PMID: 16936799. 5. Legrand D, Elass E, Carpentier M, Mazurier J. Interactions of lactoferrin with cells involved in immune function. Biochem Cell Biol. 2006 Jun;84(3):282-90. doi: 10.1139/o06-045. PMID: 16936798. 6. Takayama Y, Takezawa T. Lactoferrin promotes collagen gel contractile activity of fibroblasts mediated by lipoprotein receptors. Biochem Cell Biol. 2006 Jun;84(3):268-74. doi: 10.1139/o06-041. PMID: 16936796. 7. Saraceno R, Gramiccia T, Chimenti S, Valenti P, Pietropaoli M, Bianchi L. Topical lactoferrin can improve stable psoriatic plaque. G Ital Dermatol Venereol. 2014 Jun;149(3):335-40. PMID: 24819761. 8. Chella Krishnan K, Mukundan S, Landero Figueroa JA, Caruso JA, Kotb M. Metal-mediated modulation of streptococcal cysteine protease activity and its biological implications. Infect Immun. 2014 Jul;82(7):2992-3001. doi: 10.1128/IAI.01770-14. Epub 2014 May 5. PMID: 24799625; PMCID: PMC4097633. 9. Montesi M, Panseri S, Iafisco M, Adamiano A, Tampieri A. Coupling Hydroxyapatite Nanocrystals with Lactoferrin as a Promising Strategy to Fine Regulate Bone Homeostasis. PLoS One. 2015 Jul 6;10(7):e0132633. doi: 10.1371/journal.pone.0132633. PMID: 26148296; PMCID: PMC4492779. 10. Coussens AK, Wilkinson RJ, Martineau AR. Phenylbutyrate Is Bacteriostatic against Mycobacterium tuberculosis and Regulates the Macrophage Response to Infection, Synergistically with 25-Hydroxy-Vitamin D3. PLoS Pathog. 2015 Jul 2;11(7):e1005007. doi: 10.1371/journal.ppat.1005007. PMID: 26133770; PMCID: PMC4489717.