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MedKoo Cat#: 130488 | Name: Anrikefon

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Anrikefon is a kappa opioid receptor (KOR) agonist with an analgesic effect.

Chemical Structure

Anrikefon
Anrikefon
CAS#2269511-95-5

Theoretical Analysis

MedKoo Cat#: 130488

Name: Anrikefon

CAS#: 2269511-95-5

Chemical Formula: C39H57N7O5

Exact Mass: 703.4421

Molecular Weight: 703.93

Elemental Analysis: C, 66.54; H, 8.16; N, 13.93; O, 11.36

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Anrikefon; Anrikefon [INN]; 22SCY98BXV; UNII-22SCY98BXV; 2269511-95-5
IUPAC/Chemical Name
HSK21542; (R)-N-((R)-1-(2-acetyl-2,7-diazaspiro[3.5]nonan-7-yl)-6-amino-1-oxohexan-2-yl)-2-((R)-2-((R)-2-amino-3-phenylpropanamido)-3-phenylpropanamido)-4-methylpentanamide
InChi Key
VWXDZAZSCZVCPV-YFRBGRBWSA-N
InChi Code
InChI=1S/C39H57N7O5/c1-27(2)22-33(36(49)42-32(16-10-11-19-40)38(51)45-20-17-39(18-21-45)25-46(26-39)28(3)47)44-37(50)34(24-30-14-8-5-9-15-30)43-35(48)31(41)23-29-12-6-4-7-13-29/h4-9,12-15,27,31-34H,10-11,16-26,40-41H2,1-3H3,(H,42,49)(H,43,48)(H,44,50)/t31-,32-,33-,34-/m1/s1
SMILES Code
CC(N(C1)CC21CCN(C([C@H](NC([C@H](NC([C@H](NC([C@H](N)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)CC(C)C)=O)CCCCN)=O)CC2)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
TBD
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 703.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Wang X, Gou X, Yu X, Bai D, Tan B, Cao P, Qian M, Zheng X, Wang H, Tang P, Zhang C, Ye F, Ni J. Antinociceptive and Antipruritic Effects of HSK21542, a Peripherally-Restricted Kappa Opioid Receptor Agonist, in Animal Models of Pain and Itch. Front Pharmacol. 2021 Nov 16;12:773204. doi: 10.3389/fphar.2021.773204. PMID: 34867403; PMCID: PMC8635029.