MedKoo Cat#: 130484 | Name: SA-15-P
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

SA-15-P is an inhibitor of lymphocyte activation gene 3 (LAG-3), inhibiting both LAG-3/MHCII and LAG-3/FGL1 interactions in biochemical binding assays with IC50 values of 4.21 ± 0.84 and 6.52 ± 0.47 μM, respectively.

Chemical Structure

SA-15-P
SA-15-P
CAS#852846-00-5

Theoretical Analysis

MedKoo Cat#: 130484

Name: SA-15-P

CAS#: 852846-00-5

Chemical Formula: C26H24N2O4

Exact Mass: 428.1736

Molecular Weight: 428.49

Elemental Analysis: C, 72.88; H, 5.65; N, 6.54; O, 14.94

Price and Availability

Size Price Availability Quantity
10mg USD 550.00 2 Weeks
50mg USD 1,350.00 2 Weeks
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Related CAS #
No Data
Synonym
SA15P, SA 15 P, SA15 P, SA 15P, SA-15P, SA-15 P, SA15-P
IUPAC/Chemical Name
N-(4-(2-(1-Benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxoethoxy)phenyl)furan-2-carboxamide
InChi Key
IYGLJCOGIQDUAE-UHFFFAOYSA-N
InChi Code
InChI=1S/C26H24N2O4/c1-18-15-23(19(2)28(18)16-20-7-4-3-5-8-20)24(29)17-32-22-12-10-21(11-13-22)27-26(30)25-9-6-14-31-25/h3-15H,16-17H2,1-2H3,(H,27,30)
SMILES Code
O=C(C1=CC=CO1)NC2=CC=C(OCC(C3=C(C)N(CC4=CC=CC=C4)C(C)=C3)=O)C=C2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 428.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Abdel-Rahman SA, Rehman AU, Gabr MT. Discovery of First-in-Class Small Molecule Inhibitors of Lymphocyte Activation Gene 3 (LAG-3). ACS Med Chem Lett. 2023 Apr 11;14(5):629-635. doi: 10.1021/acsmedchemlett.3c00054. PMID: 37197466; PMCID: PMC10184155.