JH-530 Is a potent Methuosis Inducer for the Treatment of Triple-Negative Breast Cancer. JH530 showed excellent anti-proliferative activities and vacuolization capacity in TNBC. The mechanism research indicated that JH530 caused cell death through inducing methuosis of cancer cells. Furthermore, JH530 inhibited tumor growth remarkably in the HCC1806 xenograft model without an apparent decrease in body weight.
MedKoo Cat#: 123645
Name: JH530
CAS#: N/A
Chemical Formula: C22H24BrN7O2S
Exact Mass: 529.0900
Molecular Weight: 530.45
Elemental Analysis: C, 49.82; H, 4.56; Br, 15.06; N, 18.48; O, 6.03; S, 6.04
The following data is based on the product molecular weight 530.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
