MedKoo Cat#: 123602 | Name: ST-1803

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ST-1803 is a SphK inhibitor with IC50 values: 7.3 μM (SphK1), 6.5 μM (SphK2). ST-1802 is a promising candidate for further in vivo investigations and structural development.

Chemical Structure

ST-1803
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 123602

Name: ST-1803

CAS#: N/A

Chemical Formula: C10H8N4S3

Exact Mass: 279.9900

Molecular Weight: 280.38

Elemental Analysis: C, 42.84; H, 2.88; N, 19.98; S, 34.30

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ST-1803; ST 1803; ST1803
IUPAC/Chemical Name
N-(4-methylthiazol-2-yl)-[2,4'-bithiazol]-2'-amine
InChi Key
MTDICDDISWICOM-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H8N4S3/c1-6-4-16-9(12-6)14-10-13-7(5-17-10)8-11-2-3-15-8/h2-5H,1H3,(H,12,13,14)
SMILES Code
CC1=CSC(NC2=NC(C3=NC=CS3)=CS2)=N1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 280.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Vogt D, Weber J, Ihlefeld K, Brüggerhoff A, Proschak E, Stark H. Design, synthesis and evaluation of 2-aminothiazole derivatives as sphingosine kinase inhibitors. Bioorg Med Chem. 2014 Oct 1;22(19):5354-67. doi: 10.1016/j.bmc.2014.07.044. Epub 2014 Aug 6. PMID: 25150091. 2: Vitovskaia GA, Anan'eva EP, Grinberg TA, Buklova VN, Kozlov AI. Vliianie istochnikov ugleroda i azota na sintez ékzopolisakharida Cryptococcus laurentii [Effect of carbon and nitrogen sources on exopolysaccharide synthesis by Cryptococcus laurentii]. Prikl Biokhim Mikrobiol. 1983 Nov-Dec;19(6):728-32. Russian. PMID: 6664960.