MedKoo Cat#: 556325 | Name: TCS-46b
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TCS 46b is an orally active, subtype-selective GluN1A/GluN2B NMDA receptor antagonist

Chemical Structure

TCS-46b
TCS-46b
CAS#302799-86-6

Theoretical Analysis

MedKoo Cat#: 556325

Name: TCS-46b

CAS#: 302799-86-6

Chemical Formula: C22H23N3O

Exact Mass: 345.1841

Molecular Weight: 345.45

Elemental Analysis: C, 76.49; H, 6.71; N, 12.16; O, 4.63

Price and Availability

Size Price Availability Quantity
50mg USD 550.00 2 Weeks
100mg USD 950.00 2 Weeks
200mg USD 1,550.00 2 Weeks
500mg USD 2,750.00 2 Weeks
1g USD 3,850.00 2 Weeks
2g USD 6,250.00 2 Weeks
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Related CAS #
No Data
Synonym
TCS 46b; TCS-46b; TCS46b;
IUPAC/Chemical Name
5-(3-(4-benzylpiperidin-1-yl)prop-1-yn-1-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
InChi Key
JJEXWPHPFZLTCU-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H23N3O/c26-22-23-20-9-8-18(16-21(20)24-22)7-4-12-25-13-10-19(11-14-25)15-17-5-2-1-3-6-17/h1-3,5-6,8-9,16,19H,10-15H2,(H2,23,24,26)
SMILES Code
O=C2NC1=CC=C(C#CCN3CCC(CC4=CC=CC=C4)CC3)C=C1N2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 345.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Kim, J. H., Marton, J., Ametamey, S. M., & Cumming, P. (2020). A review of molecular imaging of glutamate receptors. Molecules, 25(20), 4749. Carlson, S. L. (2010). Characterization of D-aspartate receptor currents in Aplysia californica (Doctoral dissertation, University of Miami).