MedKoo Cat#: 556223 | Name: SUN24595
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

SUN24595, also known as NF-κΒ activator 1, is a potent NF-κΒ activator with an EC50 of 0.9 μM. SUN24595 induces superoxide dismutase (SOD)2 mRNA expression. SUN24595 was first reported in European Journal of Medicinal Chemistry (2021), 210, 112952. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

SUN24595
SUN24595
CAS#2387524-59-4

Theoretical Analysis

MedKoo Cat#: 556223

Name: SUN24595

CAS#: 2387524-59-4

Chemical Formula: C16H11FN2O2S

Exact Mass: 314.0525

Molecular Weight: 314.33

Elemental Analysis: C, 61.14; H, 3.53; F, 6.04; N, 8.91; O, 10.18; S, 10.20

Price and Availability

Size Price Availability Quantity
50mg USD 550.00 2 Weeks
100mg USD 950.00 2 Weeks
200mg USD 1,650.00 2 Weeks
500mg USD 2,650.00 2 Weeks
1g USD 4,250.00 2 Weeks
2g USD 6,450.00 2 Weeks
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Related CAS #
No Data
Synonym
NF-κΒ activator 1; SUN24595; SUN-24595; SUN 24595;
IUPAC/Chemical Name
3-(2-((2-fluorophenyl)amino)thiazol-4-yl)benzoic acid
InChi Key
SSUFECODNVILSX-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H11FN2O2S/c17-12-6-1-2-7-13(12)18-16-19-14(9-22-16)10-4-3-5-11(8-10)15(20)21/h1-9H,(H,18,19)(H,20,21)
SMILES Code
O=C(O)C1=CC=CC(C2=CSC(NC3=CC=CC=C3F)=N2)=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 314.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Mathew B, et al. Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-ҡB activators for the treatment of ALS [published online ahead of print, 2020 Oct 22]. Eur J Med Chem. 2020;112952 [Content Brief]