MedKoo Cat#: 556218 | Name: DKI5
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DKI5, also known as (E)-N’-benzylidenehydrazinecarbothiohydrazide, is a LOX-1 inhibitor with an IC50 value of 22.5 μM. DKI5 strongly inhibits lipid peroxidation.

Chemical Structure

DKI5
DKI5
CAS#1101130-96-4

Theoretical Analysis

MedKoo Cat#: 556218

Name: DKI5

CAS#: 1101130-96-4

Chemical Formula: C8H10N4S

Exact Mass: 194.0626

Molecular Weight: 194.26

Elemental Analysis: C, 49.46; H, 5.19; N, 28.84; S, 16.50

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
100mg USD 1,250.00 2 Weeks
200mg USD 1,950.00 2 Weeks
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Related CAS #
No Data
Synonym
Benzaldehyde, thiocarbazone; Benzaldehyde, 3-thiocarbazone; DK-I5; DK I5; DKI5; NSC137983; NSC 137983; NSC-137983;
IUPAC/Chemical Name
(E)-N'-benzylidenehydrazinecarbothiohydrazide
InChi Key
IZAXVUNREMHNOM-UXBLZVDNSA-N
InChi Code
InChI=1S/C8H10N4S/c9-11-8(13)12-10-6-7-4-2-1-3-5-7/h1-6H,9H2,(H2,11,12,13)/b10-6+
SMILES Code
NNC(N/N=C/C1=CC=CC=C1)=S
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 194.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Georgiou N, Chontzopoulou E, Cheilari A, Katsogiannou A, Karta D, Vavougyiou K, Hadjipavlou-Litina D, Javornik U, Plavec J, Tzeli D, Vassiliou S, Mavromoustakos T. Thiocarbohydrazone and Chalcone-Derived 3,4-Dihydropyrimidinethione as Lipid Peroxidation and Soybean Lipoxygenase Inhibitors. ACS Omega. 2023 Mar 21;8(13):11966-11977. doi: 10.1021/acsomega.2c07625. PMID: 37033811; PMCID: PMC10077549.