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MedKoo Cat#: 130457 | Name: RPA70N-IN-20c

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RPA70N-IN-20c inhibits protein-protein interactions by binding to RPA70N and is being used to establish replication protein A (RPA) as a potential target for cancer treatments.

Chemical Structure

RPA70N-IN-20c
RPA70N-IN-20c
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 130457

Name: RPA70N-IN-20c

CAS#: N/A

Chemical Formula: C21H15BrCl2N2O5S

Exact Mass: 555.9262

Molecular Weight: 558.22

Elemental Analysis: C, 45.18; H, 2.71; Br, 14.31; Cl, 12.70; N, 5.02; O, 14.33; S, 5.74

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
RPA70N-IN-20c
IUPAC/Chemical Name
4-bromo-2-(3-(N-(3,4-dichlorophenyl)sulfamoyl)-4-methylbenzamido)benzoic acid
InChi Key
JMFGYKWDQGHDOY-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H15BrCl2N2O5S/c1-11-2-3-12(20(27)25-18-9-13(22)4-6-15(18)21(28)29)8-19(11)32(30,31)26-14-5-7-16(23)17(24)10-14/h2-10,26H,1H3,(H,25,27)(H,28,29)
SMILES Code
O=C(O)C1=CC=C(Br)C=C1NC(C2=CC=C(C)C(S(=O)(NC3=CC=C(Cl)C(Cl)=C3)=O)=C2)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 558.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Patrone JD, Pelz NF, Bates BS, Souza-Fagundes EM, Vangamudi B, Camper DV, Kuznetsov AG, Browning CF, Feldkamp MD, Frank AO, Gilston BA, Olejniczak ET, Rossanese OW, Waterson AG, Chazin WJ, Fesik SW. Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A. ChemMedChem. 2016 Apr 19;11(8):893-9. doi: 10.1002/cmdc.201500479. Epub 2016 Jan 8. PMID: 26748787; PMCID: PMC4838552.