MedKoo Cat#: 130453 | Name: ZZL-7

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ZZL-7 produces an antidepressant effect by disrupting the interaction between the serotonin transporter (SERT) and neuronal nitric oxide synthase (nNOS) in the dorsal raphe nucleus (DRN), which in turn, enhances serotonin signaling. ZZL-7 shows promise as a potential fast-acting treatment major depressive disorder.

Chemical Structure

ZZL-7
ZZL-7
CAS#99141-91-0

Theoretical Analysis

MedKoo Cat#: 130453

Name: ZZL-7

CAS#: 99141-91-0

Chemical Formula: C11H20N2O4

Exact Mass: 244.1423

Molecular Weight: 244.29

Elemental Analysis: C, 54.08; H, 8.25; N, 11.47; O, 26.20

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ZZL-7; ZZL7; ZZL 7
IUPAC/Chemical Name
methyl acetyl-L-alanyl-L-valinate
InChi Key
RHDUVXUSBMPQOK-CBAPKCEASA-N
InChi Code
InChI=1S/C11H20N2O4/c1-6(2)9(11(16)17-5)13-10(15)7(3)12-8(4)14/h6-7,9H,1-5H3,(H,12,14)(H,13,15)/t7-,9-/m0/s1
SMILES Code
CC(C)[C@@H](C(OC)=O)NC([C@H](C)NC(C)=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 244.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Sun N, Qin YJ, Xu C, Xia T, Du ZW, Zheng LP, Li AA, Meng F, Zhang Y, Zhang J, Liu X, Li TY, Zhu DY, Zhou QG. Design of fast-onset antidepressant by dissociating SERT from nNOS in the DRN. Science. 2022 Oct 28;378(6618):390-398. doi: 10.1126/science.abo3566. Epub 2022 Oct 27. PMID: 36302033.