Alkyne-PEG6-acid, also known as 3,6,9,12,15,18-Hexaoxahexacos-25-ynoic acid, is a heterobifunctional, PEGylated crosslinker with applications in bioconjugation and as a component in the synthesis of small molecules. The crosslinker is bound at one end by a carboxyl group and an alkyne at the other. The crosslinker is referred to as 2-2-2-2-2-2-6 PROTAC® linker when it is incorporated into PROTACs, and is also used in the synthesis antibody-drug conjugates.
MedKoo Cat#: 130394
Name: Alkyne-PEG6-acid
CAS#: N/A
Chemical Formula: C20H36O8
Exact Mass: 404.2410
Molecular Weight: 404.50
Elemental Analysis: C, 59.39; H, 8.97; O, 31.64
The following data is based on the product molecular weight 404.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
