MedKoo Cat#: 130390 | Name: CCW16
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CCW16, which is the ligand for E3 ubiquitin ligase RNF4 (RING finger protein 4), is vital in the synthesis of protein degraders.

Chemical Structure

CCW16
CAS#2361138-33-0

Theoretical Analysis

MedKoo Cat#: 130390

Name: CCW16

CAS#: 2361138-33-0

Chemical Formula: C22H20ClNO3

Exact Mass: 381.1132

Molecular Weight: 381.86

Elemental Analysis: C, 69.20; H, 5.28; Cl, 9.28; N, 3.67; O, 12.57

Price and Availability

Size Price Availability Quantity
100mg USD 650.00 2 Weeks
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Related CAS #
No Data
Synonym
CCW16; CCW 16; CCW-16
IUPAC/Chemical Name
N-benzyl-2-chloro-N-(4-(4-methoxyphenoxy)phenyl)acetamide
InChi Key
DPADEQNOMBTITM-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H20ClNO3/c1-26-19-11-13-21(14-12-19)27-20-9-7-18(8-10-20)24(22(25)15-23)16-17-5-3-2-4-6-17/h2-14H,15-16H2,1H3
SMILES Code
O=C(N(CC1=CC=CC=C1)C2=CC=C(OC3=CC=C(OC)C=C3)C=C2)CCl
Appearance
To be determined
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 381.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Ward CC, Kleinman JI, Brittain SM, Lee PS, Chung CYS, Kim K, Petri Y, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Nomura DK. Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13. PMID: 31059647; PMCID: PMC7422721.