C5 Lenalidomide-PEG2-Butyl NH2 hydrochloride is a vital component in the synthesis of targeted protein degraders and PROTACs. The conjugate is composed of a Cereblon (CRBN)-recruiting ligand with alternative exit vector, a linker with both hydrophobic and hydrophilic moieties, and a pendant amine that reacts with an acid on the target warhead.
MedKoo Cat#: 130385
Name: C5 Lenalidomide-PEG2-Butyl NH2 HCl
CAS#: N/A
Chemical Formula: C23H33ClN4O6
Exact Mass: 0.0000
Molecular Weight: 496.99
Elemental Analysis: C, 55.59; H, 6.69; Cl, 7.13; N, 11.27; O, 19.32
The following data is based on the product molecular weight 496.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
