Pomalidomide-pyridine-PEG1-piperazine hydrochloride, a building block in the synthesis of targeted protein degraders and PROTACs, consists of a Cereblon (CRBN)-recruiting ligand, a linker with increased rigidity, and a pendant amine that reacts with a carboxylic acid on the target ligand.
MedKoo Cat#: 130381
Name: Pomalidomide-pyridine-PEG1-piperazine hydrochloride
CAS#: N/A
Chemical Formula: C27H31ClN6O6
Exact Mass:
Molecular Weight: 571.03
Elemental Analysis: C, 56.79; H, 5.47; Cl, 6.21; N, 14.72; O, 16.81
The following data is based on the product molecular weight 571.03 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
