(S,R,S)-VL285 Phenol-PEG1-piperazine hydrochloride is a building block for the synthesis of protein degraders and PROTACs that consists of a von Hippel-Lindau (VHL)-recruiting ligand, a semi-flexible PEG linker, and a pendant amine for reactivity with a carboxylic acid on the target ligand.
MedKoo Cat#: 130380
Name: (S,R,S)-VL285 Phenol-PEG1-piperazine hydrochloride
CAS#: N/A
Chemical Formula: C21H28ClN5O6
Exact Mass: 481.1728
Molecular Weight: 481.93
Elemental Analysis: C, 52.34; H, 5.86; Cl, 7.36; N, 14.53; O, 19.92
The following data is based on the product molecular weight 481.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
