UCM-14216 | CAS# | LPA2 antagonist

MedKoo Cat#: 123132 | Name: UCM-14216

Description:

WARNING: This product is for research use only, not for human or veterinary use.

UCM-14216 is a LPA2 antagonist

Chemical Structure

UCM-14216

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 123132

Name: UCM-14216

CAS#: N/A

Chemical Formula: C18H14Cl2N6O3

Exact Mass: 432.0500

Molecular Weight: 433.25

Elemental Analysis: C, 49.90; H, 3.26; Cl, 16.36; N, 19.40; O, 11.08

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

UCM-14216; UCM14216; UCM 14216; GLXC-26113;

IUPAC/Chemical Name

5-((2H-tetrazol-5-yl)methoxy)-2-(4-(2,4-dichlorophenoxy)-5-methyl-1H-pyrazol-3-yl)phenol

InChi Key

RZGVUGDKIXTIMM-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H14Cl2N6O3/c1-9-18(29-15-5-2-10(19)6-13(15)20)17(24-21-9)12-4-3-11(7-14(12)27)28-8-16-22-25-26-23-16/h2-7,27H,8H2,1H3,(H,21,24)(H,22,23,25,26)

SMILES Code

OC1=CC(OCC2=NNN=N2)=CC=C1C3=NNC(C)=C3OC4=CC=C(Cl)C=C4Cl

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 433.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Khiar-Fernández N, Zian D, Vázquez-Villa H, Martínez RF, Escobar-Peña A, Foronda-Sainz R, Ray M, Puigdomenech-Poch M, Cincilla G, Sánchez-Martínez M, Kihara Y, Chun J, López-Vales R, López-Rodríguez ML, Ortega-Gutiérrez S. Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice. J Med Chem. 2022 Aug 25;65(16):10956-10974. doi: 10.1021/acs.jmedchem.2c00046. Epub 2022 Aug 10. PMID: 35948083; PMCID: PMC9421655.