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MedKoo Cat#: 123116 | Name: CIDD-99

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CIDD-99 is capsazepine (CPZ) analogue with potential antitumor activity. CIDD-99, with dramatic anti-tumor effects against OSCC that may be efficacious as a lone therapy or in combination with standard therapies.

Chemical Structure

CIDD-99
CIDD-99
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 123116

Name: CIDD-99

CAS#: N/A

Chemical Formula: C24H23ClN2O2S

Exact Mass: 438.1200

Molecular Weight: 438.97

Elemental Analysis: C, 65.67; H, 5.28; Cl, 8.08; N, 6.38; O, 7.29; S, 7.30

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
CIDD-99; CIDD 99; CIDD99
IUPAC/Chemical Name
N-(4-chlorophenethyl)-6,7-dihydroxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carbothioamide
InChi Key
WZUPRTOAYRBQAC-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H23ClN2O2S/c25-19-8-6-16(7-9-19)10-12-26-24(30)27-13-11-18-14-21(28)22(29)15-20(18)23(27)17-4-2-1-3-5-17/h1-9,14-15,23,28-29H,10-13H2,(H,26,30)
SMILES Code
OC1=C(O)C=C(CCN(C(NCCC2=CC=C(Cl)C=C2)=S)C3C4=CC=CC=C4)C3=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 438.97 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sun Y, Zboril EK, De La Chapa JJ, Chai X, Da Conceicao VN, Valdez MC, McHardy SF, Gonzales CB, Singh BB. Inhibition of Ca2+ entry by capsazepine analog CIDD-99 prevents oral squamous carcinoma cell proliferation. Front Physiol. 2022 Sep 15;13:969000. doi: 10.3389/fphys.2022.969000. PMID: 36187775; PMCID: PMC9521718. 2: De La Chapa JJ, Singha PK, Self KK, Sallaway ML, McHardy SF, Hart MJ, McGuff HS, Valdez MC, Ruiz F 2nd, Polusani SR, Gonzales CB. The novel capsazepine analog, CIDD-99, significantly inhibits oral squamous cell carcinoma in vivo through a TRPV1-independent induction of ER stress, mitochondrial dysfunction, and apoptosis. J Oral Pathol Med. 2019 May;48(5):389-399. doi: 10.1111/jop.12843. Epub 2019 Apr 4. PMID: 30825343; PMCID: PMC6506371.