Pomalidomide-PEG2-C2-NH2 HCl, a functionalized cereblon ligand, has applications in the development of pomalidomide-based PROTACs, furthermore playing a key role in the development of a protein degrader library. The amine group on Pomalidomide-PEG2-C2-NH2 HCl has been shown to lead to the rapid conjugation with carboxyl linkers through the process of coupling reactions.
MedKoo Cat#: 130368
Name: Pomalidomide-PEG2-C2-NH2 HCl
CAS#: 2245697-87-2
Chemical Formula: C19H25ClN4O6
Exact Mass: 440.1463
Molecular Weight: 440.88
Elemental Analysis: C, 51.76; H, 5.72; Cl, 8.04; N, 12.71; O, 21.77
The following data is based on the product molecular weight 440.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
