RPF101 | CAS# | Capsaicin-like analogue

MedKoo Cat#: 123112 | Name: RPF101

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RPF101 is a new capsaicin-like analogue. RPF101 disrupts the microtubule network accompanied by arrest in the G2/M phase, inducing apoptosis and mitotic catastrophe in the MCF-7 breast cancer cells.

Chemical Structure

RPF101

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 123112

Name: RPF101

CAS#: N/A

Chemical Formula: C14H13NO4S

Exact Mass: 291.0600

Molecular Weight: 291.32

Elemental Analysis: C, 57.72; H, 4.50; N, 4.81; O, 21.97; S, 11.01

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

RPF101; RPF 101; RPF-101

IUPAC/Chemical Name

N-(benzo[d][1,3]dioxol-5-ylmethyl)benzenesulfonamide

InChi Key

YMEAPJBSAMZMRR-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H13NO4S/c16-20(17,12-4-2-1-3-5-12)15-9-11-6-7-13-14(8-11)19-10-18-13/h1-8,15H,9-10H2

SMILES Code

O=S(NCC1=CC=C2C(OCO2)=C1)(C3=CC=CC=C3)=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 291.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: de-Sá-Júnior PL, Pasqualoto KF, Ferreira AK, Tavares MT, Damião MC, de Azevedo RA, Câmara DA, Pereira A, de Souza DM, Parise Filho R. RPF101, a new capsaicin-like analogue, disrupts the microtubule network accompanied by arrest in the G2/M phase, inducing apoptosis and mitotic catastrophe in the MCF-7 breast cancer cells. Toxicol Appl Pharmacol. 2013 Feb 1;266(3):385-98. doi: 10.1016/j.taap.2012.11.029. Epub 2012 Dec 10. PMID: 23238560. 2: Chaves OA, Tavares MT, Cunha MR, Parise-Filho R, Sant'Anna CMR, Netto- Ferreira JC. Multi-Spectroscopic and Theoretical Analysis on the Interaction between Human Serum Albumin and a Capsaicin Derivative-RPF101. Biomolecules. 2018 Aug 23;8(3):78. doi: 10.3390/biom8030078. PMID: 30142945; PMCID: PMC6164054.