Pomalidomide-PEG2-azide is vital in the synthesis of protein degraders and in the development of PROTACs, consisting of a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant azide for use in click chemistry.
MedKoo Cat#: 130363
Name: Pomalidomide-PEG2-azide
CAS#: 2267306-14-7
Chemical Formula: C19H20N6O7
Exact Mass: 444.1393
Molecular Weight: 444.40
Elemental Analysis: C, 51.35; H, 4.54; N, 18.91; O, 25.20
The following data is based on the product molecular weight 444.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |