RL-603 | CAS#444904-63-6 | PDE3 inhibitor

MedKoo Cat#: 123092 | Name: RL-603

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RL-603 is a PDE3 inhibitor.

Chemical Structure

RL-603

CAS#444904-63-6

Theoretical Analysis

MedKoo Cat#: 123092

Name: RL-603

CAS#: 444904-63-6

Chemical Formula: C8H7Cl2N3

Exact Mass: 215.0000

Molecular Weight: 216.07

Elemental Analysis: C, 44.47; H, 3.27; Cl, 32.81; N, 19.45

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

BD898EX8IE; CHEMBL1548; RL603; RL-603; RL 603

IUPAC/Chemical Name

5,6-dichloro-3,4-dihydroquinazolin-2-amine

InChi Key

VBKOTIVQMCTTAQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C8H7Cl2N3/c9-5-1-2-6-4(7(5)10)3-12-8(11)13-6/h1-2H,3H2,(H3,11,12,13)

SMILES Code

NC1=NC2=CC=C(Cl)C(Cl)=C2CN1

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 216.07 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Erusalimsky JD, Hong Y, Franklin R. Is the platelet lowering activity of anagrelide mediated by its major metabolite 2-amino-5,6-dichloro-3,4-dihydroquinazoline (RL603)? Exp Hematol. 2002 Jul;30(7):625-6; author reply 626-7. doi: 10.1016/s0301-472x(02)00870-6. PMID: 12135656.