Synonym
4-(Maleinimido)phenyl isocyanate; PMPI; 4-(Maleinimido)phenyl isocyanate; p-Maleimidophenyl isocyanate
IUPAC/Chemical Name
1-(4-isocyanatophenyl)-1H-pyrrole-2,5-dione
InChi Key
OJQSISYVGFJJBY-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H6N2O3/c14-7-12-8-1-3-9(4-2-8)13-10(15)5-6-11(13)16/h1-6H
SMILES Code
O=C(N1C2=CC=C(N=C=O)C=C2)C=CC1=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
214.18
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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7: Coyne CP, Jones T, Pharr T. Synthesis of a covalent gemcitabine-(carbamate)-[anti-HER2/neu] immunochemotherapeutic and its cytotoxic anti-neoplastic activity against chemotherapeutic-resistant SKBr-3 mammary carcinoma. Bioorg Med Chem. 2011 Jan 1;19(1):67-76. doi: 10.1016/j.bmc.2010.11.046. Epub 2010 Nov 25. PMID: 21169024.
8: Cha TW, Boiadjiev V, Lozano J, Yang H, Zhu XY. Immobilization of oligonucleotides on poly(ethylene glycol) brush-coated Si surfaces. Anal Biochem. 2002 Dec 1;311(1):27-32. doi: 10.1016/s0003-2697(02)00399-8. PMID: 12441149.
