MedKoo Cat#: 123062 | Name: (E/Z)-NSAH
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(E/Z)-NSAH is an isoform of NSAH, which is reversible and competitive nonnucleoside ribonucleotide reductase (RR) inhibitor.

Chemical Structure

(E/Z)-NSAH
(E/Z)-NSAH
CAS#54009-54-0

Theoretical Analysis

MedKoo Cat#: 123062

Name: (E/Z)-NSAH

CAS#: 54009-54-0

Chemical Formula: C18H14N2O3

Exact Mass: 306.1004

Molecular Weight: 306.32

Elemental Analysis: C, 70.58; H, 4.61; N, 9.15; O, 15.67

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
200mg USD 1,250.00 2 Weeks
500mg USD 2,650.00 2 Weeks
1g USD 3,650.00 2 Weeks
2g USD 5,950.00 2 Weeks
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Related CAS #
No Data
Synonym
HNASH; NSAH; (E/Z)-NSAH
IUPAC/Chemical Name
(E)-2-hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)benzohydrazide
InChi Key
ZZSJOLDICPVVAV-YBFXNURJSA-N
InChi Code
InChI=1S/C18H14N2O3/c21-16-8-4-3-7-14(16)18(23)20-19-11-15-13-6-2-1-5-12(13)9-10-17(15)22/h1-11,21-22H,(H,20,23)/b19-11+
SMILES Code
C1=CC=C2C(=C1)C=CC(=C2C=NNC(=O)C3=CC=CC=C3O)O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 306.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Ahmad MF, Alam I, Huff SE, Pink J, Flanagan SA, Shewach D, Misko TA, Oleinick NL, Harte WE, Viswanathan R, Harris ME, Dealwis CG. Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule. Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8241-8246. doi: 10.1073/pnas.1620220114. Epub 2017 Jul 17. Erratum in: Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30858. doi: 10.1073/pnas.2021828117. PMID: 28716944; PMCID: PMC5547592.