MedKoo Cat#: 130343 | Name: TCO-amine HCl salt
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TCO-amine HCl salt is an agent with applications in biological labeling and imaging by reacting with 1; 2; 4; 5-tetrazines for ligation.

Chemical Structure

TCO-amine HCl salt
TCO-amine HCl salt
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 130343

Name: TCO-amine HCl salt

CAS#: N/A

Chemical Formula: C12H23ClN2O2

Exact Mass:

Molecular Weight: 262.78

Elemental Analysis: C, 54.85; H, 8.82; Cl, 13.49; N, 10.66; O, 12.18

Price and Availability

Size Price Availability Quantity
10mg USD 600.00 2 Weeks
50mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
TCO-amine HCl salt; trans-Cyclooctene-amine hydrochloride salt; TCO-NH2, HCl salt
IUPAC/Chemical Name
(E)-cyclooct-4-en-1-yl (3-aminopropyl)carbamate hydrochloride
InChi Key
GIYQQURLGCGUKK-TYYBGVCCSA-N
InChi Code
InChI=1S/C12H22N2O2.ClH/c13-9-6-10-14-12(15)16-11-7-4-2-1-3-5-8-11;/h1-2,11H,3-10,13H2,(H,14,15);1H/b2-1+;
SMILES Code
O=C(OC1CCC/C=C/CC1)NCCCN.[H]Cl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 262.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Karver MR, Weissleder R, Hilderbrand SA. Synthesis and evaluation of a series of 1,2,4,5-tetrazines for bioorthogonal conjugation. Bioconjug Chem. 2011 Nov 16;22(11):2263-70. doi: 10.1021/bc200295y. Epub 2011 Oct 24. PMID: 21950520; PMCID: PMC3254257. 2. Blackman ML, Royzen M, Fox JM. Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity. J Am Chem Soc. 2008 Oct 15;130(41):13518-9. doi: 10.1021/ja8053805. Epub 2008 Sep 18. PMID: 18798613; PMCID: PMC2653060. 3. Devaraj NK, Weissleder R, Hilderbrand SA. Tetrazine-based cycloadditions: application to pretargeted live cell imaging. Bioconjug Chem. 2008 Dec;19(12):2297-9. doi: 10.1021/bc8004446. PMID: 19053305; PMCID: PMC2677645.