MedKoo Cat#: 556211 | Name: LDH-IN-2
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

LDH-IN-2 is an inhibitor of glycolate oxidase.

Chemical Structure

LDH-IN-2
LDH-IN-2
CAS#893739-96-3

Theoretical Analysis

MedKoo Cat#: 556211

Name: LDH-IN-2

CAS#: 893739-96-3

Chemical Formula: C11H8O4

Exact Mass: 204.0423

Molecular Weight: 204.18

Elemental Analysis: C, 64.71; H, 3.95; O, 31.34

Price and Availability

Size Price Availability Quantity
100mg USD 1,350.00 2 Weeks
1g USD 4,250.00 2 Weeks
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Related CAS #
No Data
Synonym
LDH-IN-2; LDH IN-2; LDH-IN 2; LDH IN 2
IUPAC/Chemical Name
Benzoic acid, 5-(2-furanyl)-2-hydroxy-
InChi Key
HLMCSUKQRLAWJT-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H8O4/c12-9-4-3-7(6-8(9)11(13)14)10-2-1-5-15-10/h1-6,12H,(H,13,14)
SMILES Code
O=C(O)C1=CC(C2=CC=CO2)=CC=C1O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Primary hyperoxaluria type 1 (PH1) is a rare life-threatening genetic disease related to glyoxylate metabolism and characterized by accumulation of calcium oxalate crystals. Current therapies involve hepatic and/or renal transplantation, procedures that have significant morbidity and mortality and require long-term immunosuppression. Thus, a pharmacol. treatment is urgently needed

Preparing Stock Solutions

The following data is based on the product molecular weight 204.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Moya-Garzón MD, Martín Higueras C, Peñalver P, Romera M, Fernandes MX, Franco-Montalbán F, Gómez-Vidal JA, Salido E, Díaz-Gavilán M. Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1. J Med Chem. 2018 Aug 23;61(16):7144-7167. doi: 10.1021/acs.jmedchem.8b00399. Epub 2018 Aug 6. PMID: 30028141.