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MedKoo Cat#: 122974 | Name: OF-C4-Deg-Lin
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

OF-C4-Deg-Lin has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA in vitro and in vivo. OF-C4-Deg-Lin delivers anti-FLuc siRNA and FLuc mRNA more efficiently in HeLa cells than OF-Deg-Lin.

Chemical Structure

OF-C4-Deg-Lin
OF-C4-Deg-Lin
CAS#1853203-01-6

Theoretical Analysis

MedKoo Cat#: 122974

Name: OF-C4-Deg-Lin

CAS#: 1853203-01-6

Chemical Formula: C100H176N4O10

Exact Mass: 1593.3400

Molecular Weight: 1594.53

Elemental Analysis: C, 75.33; H, 11.13; N, 3.51; O, 10.03

Price and Availability

Size Price Availability Quantity
1mg USD 550.00 2 Weeks
5mg USD 1,050.00 2 Weeks
10mg USD 1,550.00 2 Weeks
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Related CAS #
No Data
Synonym
OF-C4-Deg-Lin; SCHEMBL17401299
IUPAC/Chemical Name
(((3,6-dioxopiperazine-2,5-diyl)bis(butane-4,1-diyl))bis(azanetriyl))tetrakis(butane-4,1-diyl) (9Z,9'Z,9''Z,9'''Z,12Z,12'Z,12''Z,12'''Z)-tetrakis(octadeca-9,12-dienoate)
InChi Key
ZQXDXCNSODVUPG-RGLFHLPNSA-N
InChi Code
InChI=1S/C100H176N4O10/c1-5-9-13-17-21-25-29-33-37-41-45-49-53-57-61-79-95(105)111-89-73-69-85-103(86-70-74-90-112-96(106)80-62-58-54-50-46-42-38-34-30-26-22-18-14-10-6-2)83-67-65-77-93-99(109)102-94(100(110)101-93)78-66-68-84-104(87-71-75-91-113-97(107)81-63-59-55-51-47-43-39-35-31-27-23-19-15-11-7-3)88-72-76-92-114-98(108)82-64-60-56-52-48-44-40-36-32-28-24-20-16-12-8-4/h21-28,33-40,93-94H,5-20,29-32,41-92H2,1-4H3,(H,101,110)(H,102,109)/b25-21-,26-22-,27-23-,28-24-,37-33-,38-34-,39-35-,40-36-
SMILES Code
O=C1NC(CCCCN(CCCCOC(CCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCOC(CCCCCCC/C=C\C/C=C\CCCCC)=O)C(NC1CCCCN(CCCCOC(CCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCOC(CCCCCCC/C=C\C/C=C\CCCCC)=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,594.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Fenton, O. S., Kauffman, K. J., McClellan, R. L., Kaczmarek, J. C., Zeng, M. D., Andresen, J. L., ... & Anderson, D. G. (2018). Customizable lipid nanoparticle materials for the delivery of siRNAs and mRNAs. Angewandte Chemie International Edition, 57(41), 13582-13586. 2: Xu, Y., Golubovic, A., Xu, S., Pan, A., & Li, B. (2023). Rational design and combinatorial chemistry of ionizable lipids for RNA delivery. Journal of Materials Chemistry B, 11(28), 6527-6539. 3: Lin, L., Su, K., Cheng, Q., & Liu, S. (2023). Targeting materials and strategies for RNA delivery. Theranostics, 13(13), 4667.