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MedKoo Cat#: 130293 | Name: (S)-SW228703

Description:

WARNING: This product is for research use only, not for human or veterinary use.

(S)-SW228703 is an antimalarial agent that displays asexual blood and liver stage activity.

Chemical Structure

(S)-SW228703
(S)-SW228703
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 130293

Name: (S)-SW228703

CAS#: N/A

Chemical Formula: C20H24N2O3

Exact Mass: 340.1787

Molecular Weight: 340.42

Elemental Analysis: C, 70.57; H, 7.11; N, 8.23; O, 14.10

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
(S)-SW228703; (S) SW228703; (S)-SW703; (S) SW703
IUPAC/Chemical Name
(S)-2-amino-1-(3-(2,6-dimethylphenoxy)azetidin-1-yl)-3-(4-hydroxyphenyl)propan-1-one
InChi Key
SJVCGKIKSCAMSK-SFHVURJKSA-N
InChi Code
InChI=1S/C20H24N2O3/c1-13-4-3-5-14(2)19(13)25-17-11-22(12-17)20(24)18(21)10-15-6-8-16(23)9-7-15/h3-9,17-18,23H,10-12,21H2,1-2H3/t18-/m0/s1
SMILES Code
O=C(N1CC(OC2=C(C)C=CC=C2C)C1)[C@@H](N)CC3=CC=C(O)C=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 340.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Imlay LS, Lawong AK, Gahalawat S, Kumar A, Xing C, Mittal N, Wittlin S, Churchyard A, Niederstrasser H, Crespo-Fernandez B, Posner BA, Gamo FJ, Baum J, Winzeler EA, Laleu B, Ready JM, Phillips MA. Fast-Killing Tyrosine Amide ((S)-SW228703) with Blood- and Liver-Stage Antimalarial Activity Associated with the Cyclic Amine Resistance Locus (PfCARL). ACS Infect Dis. 2023 Mar 10;9(3):527-539. doi: 10.1021/acsinfecdis.2c00527. Epub 2023 Feb 10. PMID: 36763526.

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