JR2-298 is a σ2R ligand that binds to σ2R with a Ki of 10 nM. JR2-298 shows promise as a potential treatment for pancreatic cancer, as σ2R is often overexpressed in cancers, making it the ideal target for preventing/reducing tumor proliferation.
MedKoo Cat#: 130278
Name: JR2-298
CAS#: N/A
Chemical Formula: C23H29FN6O
Exact Mass: 424.2387
Molecular Weight: 424.52
Elemental Analysis: C, 65.07; H, 6.89; F, 4.48; N, 19.80; O, 3.77
The following data is based on the product molecular weight 424.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
