MedKoo Cat#: 122911 | Name: Fluostatin B
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fluostatin B is a fluorenone originally found in Streptomyces.1 It inhibits dipeptidyl peptidase 3 (DPP-3; IC50 = 24 µg/ml).

Chemical Structure

Fluostatin B
Fluostatin B
CAS#158906-40-2

Theoretical Analysis

MedKoo Cat#: 122911

Name: Fluostatin B

CAS#: 158906-40-2

Chemical Formula: C18H14O6

Exact Mass: 326.0800

Molecular Weight: 326.30

Elemental Analysis: C, 66.26; H, 4.32; O, 29.42

Price and Availability

Size Price Availability Quantity
1mg USD 850.00 2 Weeks
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Related CAS #
No Data
Synonym
Fluostatin B; Fluostatin-B; FluostatinB
IUPAC/Chemical Name
2,3-dihydro-1,2,6,7-tetrahydroxy-3-methyl-1H-benzo[a]fluorene-4,11-dione
InChi Key
PLKATXVLQJQTSA-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H14O6/c1-6-15(21)8-5-10(20)13-11-7(3-2-4-9(11)19)17(23)14(13)12(8)18(24)16(6)22/h2-6,16,18-20,22,24H,1H3
SMILES Code
O=C1C(C)C(O)C(O)C2=C1C=C(O)C(C3=C4C=CC=C3O)=C2C4=O
Appearance
To be determined
Purity
>90% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 326.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Akiyama T, Nakamura KT, Takahashi Y, Naganawa H, Muraoka Y, Aoyagi T, Takeuchi T. Fluostatins A and B, new inhibitors of dipeptidyl peptidase III, produced by Streptomyces sp. TA-3391. II. Structure determination. J Antibiot (Tokyo). 1998 Jun;51(6):586-8. doi: 10.7164/antibiotics.51.586. PMID: 9711223.