JC2-11 is a pan-inflammasome inhibitor, with the potential to serve as a key agent in the treatment of certain cancers and metabolic disorders that are a result of dysregulated inflammasome activation. JC2-11 was found to inhibit both (IL)-1β and lactate dehydrogenases secretion, as well as caspase-1 activity.
MedKoo Cat#: 130221
Name: JC2-11
CAS#: 937820-89-8
Chemical Formula: C17H15FO4
Exact Mass: 302.0954
Molecular Weight: 302.30
Elemental Analysis: C, 67.54; H, 5.00; F, 6.28; O, 21.17
The following data is based on the product molecular weight 302.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
