GJ2 is an irreversible inhibitor of GLS1 activity, specifically targeting the K320 residue. GJ2 treatment resulted in the reduction in the growth rate of cancer cells, trypsin digestion of KGA, and the formation of clonal tumor cells.
MedKoo Cat#: 130210
Name: GJ2
CAS#: N/A
Chemical Formula: C27H25N7O4Se
Exact Mass: 591.1133
Molecular Weight: 590.50
Elemental Analysis: C, 54.92; H, 4.27; N, 16.60; O, 10.84; Se, 13.37
The following data is based on the product molecular weight 590.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
